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Polydnavirus Histone H4 and its role in insect immunity

Language EnglishEnglish
Book Paperback
Book Polydnavirus Histone H4 and its role in insect immunity Wael Gad
Libristo code: 06943390
Publishers LAP Lambert Academic Publishing, November 2011
Cotesia plutellae (Braconidae: Hymenoptera) is a solitary endoparasitoid wasp that parasitizes the d... Full description
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Cotesia plutellae (Braconidae: Hymenoptera) is a solitary endoparasitoid wasp that parasitizes the diamondback moth, Plutella xylostella (L.) (Yponomeutidae: Lepidoptera). For successful parasitization, its symbiotic polydnavirus (CpBV) helps the wasps to attenuate host immune capacity and manipulate host developmental physiology. An analysis of CpBV genome sequence indicated the presence of one putative gene (CpBV-H4) showing a high similarity to histone H4. Histone H4, one of the four histone subunits along with H2A, H2B and H3, forms an eukaryotic nucleosome core. Along with H3, it plays a central role in nucleosome formation. CpBV-H4 showed expression in different tissues in parasitized P. xylostella. Transient expression of CpBV-H4 in nonparasitized P. xylostella resulted in significant impairment of hemocyte-spreading and decreased gene expression of host H4, while knock-down of the transient expression using double-stranded RNA interference recovered the immune capacity and gene expression.

About the book

Full name Polydnavirus Histone H4 and its role in insect immunity
Author Wael Gad, Yonggyun Kim
Language English
Binding Book - Paperback
Date of issue 2012
Number of pages 88
EAN 9783659243981
Libristo code 06943390
Publishers LAP Lambert Academic Publishing
Weight 149
Dimensions 150 x 220 x 5
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