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NMDA Antagonists as Potential Analgesic Drugs

Language EnglishEnglish
Book Hardback
Book NMDA Antagonists as Potential Analgesic Drugs Dalip J.S. Sirinathsinghji
Libristo code: 01716394
Publishers Birkhauser Verlag AG, January 2002
There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involv... Full description
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There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involved in the transmission of nociceptive information and in the triggering mechanisms for hyperalgesia and allodynia. This evidence allows rational development of a new class of analgesic drugs that act as antagonists of the NMDA receptor, supported by emerging evidence with existing excitatory amino acid antagonists.§Leading scientists in excitatory amino acid and analgesia research have compiled in this volume the most recent information on molecular biology, physiology and pharmacology of NMDA receptors, their neuroanatomical localisation within specific neural pathways involved in nociception, and experimental and clinical evidence demonstrating the potential of receptor antagonists of NMDA and other excitatory amino acids in the treatment of pain states.

About the book

Full name NMDA Antagonists as Potential Analgesic Drugs
Author Dalip J.S. Sirinathsinghji, Ray G. Hill
Language English
Binding Book - Hardback
Date of issue 2002
Number of pages 194
EAN 9783764360115
ISBN 3764360119
Libristo code 01716394
Publishers Birkhauser Verlag AG
Weight 600
Dimensions 155 x 235 x 17

Categories

Medicine & Nursing > Medical specialties, branches of medicine > Anaesthetics > Pain & pain management
Medicine & Nursing > Medical specialties, branches of medicine > Pharmacology
Medicine & Nursing > Medical specialties, branches of medicine > Neurology & clinical neurophysiology
Medicine & Nursing > Medicine: general issues
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