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Osteoporosis is a major concern all over the world. Therefore, the major aim of our study is to focus on this popular disease and its correlation with aging, a gradual loss of bone mass and results in osteopenia and osteoporosis. Heritable factors account for 60-80% of optimal bone mineralization. Modifiable factors, such as weight-bearing exercise, nutrition, body mass, and hormonal milieu, play an important role in the development of osteopenia and osteoporosis in adulthood. Currently, anti-osteoporosis agents, including estrogen, bisphosphonates, and selective estrogen receptor modulators (SERMs), are the drugs of choice for osteoporosis. Other treatments include parathyroid hormone (PTH) as well as the nutritional support of calcium and vitamin D. Taking into consideration that Osteoporosis is a silent disease we will introduce a new device for early detection which are used worldwide and to follow up therapy. Finally, we will highlight a new link in between one therapy of this disease which could be a potential treatment for Corona epidemic crises.