Protective Arm of the Renin Angiotensin System (RAS)

The Protective Arm of the RAS: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of the renin-angiotensin system (RAS) providing readers with early insight into a system which will become of major medical importance. It is extensively demonstrated that the RAS, when over activated, represents a disease-promoting and disease-sustaining system. But recently the protective role of the RAS has emerged supported by a large number of experimental studies. In fact, specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1-7) peptide with its receptor Mas, and the enzyme ACE 2 exert significant beneficial actions by counter-balancing the well-known harmful side of the RAS. * Provides a complete understanding of the protective, beneficial role of the Renin Angiotensin System (RAS).* Combines the knowledge of editors who pioneered research on protective renin angiotensin system including Dr. Robson Santos who discovered angiotensins-(1-7) and its receptor Mas; and Dr. U. Muscha Steckelings and Dr. Thomas Unger who made contributions to AT2 receptor research and were the first to use a novel specific AT2-antagonist in preclinical studies.* Shows the protective RAS axes are able to ameliorate the course of several cardiovascular, renal and neurological diseases.