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At once a comprehensive handbook for the active researcher and a thorough introduction for the advanced student, this reference provides: Coverage of wide range of applications, including agricultural sciences, animal and biomedi-cal sciences, and industrial and engineering studies Information on new developments in the design of fractional factorials with non-prime numbers of levels in mixed-level fractional factorials Detailed information on the construction of plans and the relationships among categories of designs Thorough discussion of balanced, partially balanced, lattice, cyclic and alpha-designs Accommodations for how to evaluate the power and efficiency of designs that are not perfectly balanced Unified and simplified presentation of general forms for estimation and hypothesis testing