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The numerical optimization of practical applications has been an issue of major importance for the last 10 years. It allows us to explore reliable non-trivial configurations, differing widely from all known solutions. The purpose of this book is to introduce the state-of-the-art concerning this issue and many complementary applications are presented.The numerical optimization of practical applications is an issue of growing importance in research and industry. It allows both the exploration of non-trivial configurations differing widely from all known solutions and the step-by-step improvement of existing designs. §The purpose of this book is to introduce the state of the art concerning this issue, referred to in the book as CFD-based Optimization (CFD-O). Many complementary applications are presented, so that interested researchers and engineers will get a clear view of the present possibilities for all problems where the numerical optimization process relies on evaluations obtained through Computational Fluid Dynamics.