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This text outlines the potential of the microbial catalyst for present and future microbial process development without waste formation, leading to a clean environment. It is intended to inspire scientists and biochemical engineers to isolate new micro-organisms from nature and to explore the optimal potential of the genotype before altering its code through genetical engineenng. The book is structured to encourage the reader to use basic scientific and biochemical engineering concepts for the development of new and improved fermentation technology industries. It leads the reader from aspects of isolation, identification and preservation of microbial strains to the use of thermodynamics and their biochemistry to the final end-products and their purification. Special emphasis is given to the restoration of our present, and the preservation of our future, environment using socio-ecological biotechnological concepts.