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This textbook introduces the mathematical concepts and methods that underlie statistics. The course is unified, in the sense that no prior knowledge of probability theory is assumed, being developed as needed. The book is committed to both a high level of mathematical seriousness and to an intimate connection with application. In its teaching style, the book is mathematically complete, concrete, constructive, active. The text is aimed at the upper undergraduate or the beginning Masters program level. It assumes the usual two-year college mathematics sequence, including an introduction to multiple integrals, matrix algebra, and infinite series.