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Infertility causes dishermony and distress of life With a social disgrace in our country.pcos is a reletively common disease affecting 15% of infertile women.there is strong association between pco and subfertility due to anovulation.ln cc resistant pcos Patients both LOD and gonadotropin are equally effective but LOD offer the oppertunity to favor ovarian follicular development for at least six cycles.lt improves clinical and biochemical parameters significantly and also increases the ovulation and pregnancy rate.we are sure that this book will be great help to all practitioners looking for workable solutions.sincere thanksfor constant support and appreciation to all our contributors to get this publications ready.lastly to all our spouses and children for bearing with ous in our endeavor.