Jak nakupovat
Doručení
Nákupní rádce
Imaging AMPA-Type Receptors in Hippocampal Neurons
Angličtina
165 b
30 dní na vrácení zboží
Mohlo by vás také zajímat
Synaptic plasticity is the ability of the §connections between nerve §cells, called synapses, to change in strength. The §presence of the §AMPA-type glutamate receptors at the synapse §controls the strength §of excitatory transmission and their number can be §modulated. §There is however a need in technologies to visualize §these events.§In this study, a recently established protein-§labeling technique was §applied to label individually AMPA receptor subunits §at the surface of §neurons. Moreover, these subunits are §integrated into heteromeric receptors and targeted §to functional §synapses. The diffusion of receptors at the surface §of living neurons §was dependent on the subunit composition. §High-resolution images, sub-difraction limited, of §hippocampal §neurons stained for GluR2 were acquired with an §experimental §scanning near-field optical microscopy (SNOM) with §the aim to §image single molecules.§§This study should help to shed some light on the §molecular aspects §of the synaptic plasticity and could be particularly §interesting to neuroscientists and physicists §interesting in life sciences §applications.
Informace o knize
Angličtina
Kategorie
