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HMG-CoA reductase inhibitors (statins) are established drugs for the §treatment of hypercholesterolemia. Furthermore, they induce regression §of vascular atherosclerosis as well as reduction of §cardiovascular-related morbidity and death in patients with and without §coronary artery disease. This book deals with statins which have §substantially altered the approach to therapy of atherosclerosis and its §sequelae. Emphasis is placed on the scientific background to the §discoveries and the development of the therapy, including an overview of §the current state of knowledge of the drugs. Clinical data are reviewed §extensively. This book not only provides the reader with valuable §information but also stimulates further research into the pathogenesis §of atherosclerosis and the mechanisms behind the action of effective §statins. It sets the stage for creative thinking among scientists of §many disciplines for the accomplishment of our ultimate goals in §treating atherosclerosis and its sequelae. This topical volume...