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This extensive handbook is indispensible for clinicians and physicians. It provides assistance in the establishment of a precise diagnosis and in the decision of adequate patient treatment. Up-to-date and comprehensive information for the differential diagnosis by laboratory medicine is presented in a well-structured manner. Described in different sections are data of more than 1950 different conditions, the interference of over 1200 different drugs as well as a comprehensive section of international reference values of clinical-biochemical and laboratory parameters. The detailed index of more than 900 biochemical/laboratory parameters in various biological samples is especially indispensible for the practitinor and the extensive list of frequently used synonyms and abbreviations provide comfortable and fast access to desired information.