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This volume provides a comprehensive overview of the present state of art on classification, neuropathology, pathogenesis, clinical features, diagnosis and old and new promising therapeutic drug strategies of idiopathic Parkinson's disease. Articles focus on new aspects of preclinical course and symptomatology, subtypes with their impact on the pathology, genetic alterations, novel mechanisms of neuronal cell death, diagnostic tools and old and novel therapeutic approaches with respect to neuroprotection and neuroregeneration in Parkinson's disease. Particular emphasis has been placed on a novel antiparkinsonian drug called budipine with various modes of action also influencing altered non dopaminergic systems in Parkinson's disease. This work is an exhaustive up-to-date compendium, that assembles the entire spectrum of current basic and clinical research in Parkinson's disease.