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The goal of the second edition of the Clinical Handbook of Insomnia is to update and expand on the previous edition by presenting the latest developments in the field of insomnia and by involving more thought leaders from around the world. Over the past 4 years there has been an increasing amount of data regarding the pathophysiology of insomnia and there have been significant advancements in its treatment with FDA approval of 4 new medications for it and the development of several others that are going to be available in the next 5 years.