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Biomarkers in periodontal disease
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Acute periodontitis is known as the 6th most common disease affecting more than 740 million people worldwide. The diagnosis of periodontal disease is highly dependent on the examination of normal clinical parameters. However, they symbolize the past, rather than the present, or the progression of the disease and the clinical condition, the potential consequence of periodontal treatment. In some cases periodontal disease and critical biomarkers have been extensively tested to address these problems and other biomarkers have been interpreted as point-of-care (PoC) tests. The main purpose of this book is to provide an overview of the various biomarkers in diagnosing and controlling periodontal diseases. Among the improved PoC tests to date, the active matrix metalloproteinase-8 showed promising results regarding diagnostic and predictive values. On the other hand, further research is needed to increase sensitivity and clarity by combining more than one biomarker with the integration of these test kits with periodontal risk assessments.
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