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Acute exercise reduces triglycerides (TG) and §increases high-density lipoprotein cholesterol (HDL-§C) and HDL2-C in both men and women. Acute effects §of moderate intensity walking on plasma lipids and §lipoproteins of obese Black and White women were §invstigated. Energy expenditure of either 300 or 500 §kcal was not sufficient to change TC, LDL-C, HDL-C, §HDL3-C, and HDL2-C in obese women. Triglycerides §were increased immediately post exercise and §returned to baseline at 24 and 48hrs after exercise. §The magnitude of change in TG was dependent on the §amount of energy expended. Plasma HDL-C and HDL2-C §of obese women seem to be resistant to the increase §usually observed with acute exercise in non-obese §women. Obese women responded with increased TG §immediately post exercise as opposed to the decrease §usually observed immediately post exercise in non-§obese women. A different response by obese women may §be due to the effect obesity has on blood lipid and§lipoprotein metabolism.